Description

2,3,4,5,6-Pentamethylbenzyl Alcohol is a highly substituted benzyl alcohol derivative characterized by its unique sterically hindered structure. This compound matters as a versatile and valuable synthetic intermediate, particularly in the production of advanced organic materials and fine chemicals. It is primarily needed by R&D chemists and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly where steric bulk is required to modulate biological activity or metabolic stability.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized phosphine or N-heterocyclic carbene (NHC) ligands used in homogeneous catalysis.
• Advanced Material Synthesis: A key building block for creating dendrimers, liquid crystals, and organic frameworks where its multi-methylated structure imparts specific solubility and packing properties.
• Agrochemical Research: Employed in developing novel pesticides and herbicides, leveraging its hydrophobic character to influence compound uptake and persistence.
• Fine Chemical Production: Acts as a precursor for fragrances, dyes, and other specialty chemicals requiring a hindered benzyl moiety.
• Polymer Modification: Used to introduce functional, bulky side chains into polymers to alter thermal properties, glass transition temperatures, and material toughness.

Basic Information

Product Name	2,3,4,5,6-Pentamethylbenzyl Alcohol
CAS No.	484-66-2
Molecular Formula	C12H18O
Molecular Weight	178.27 g/mol
Synonyms	(2,3,4,5,6-Pentamethylphenyl)methanol; Pentamethylbenzyl Alcohol; Benzyl alcohol, 2,3,4,5,6-pentamethyl-; 2,3,4,5,6-Pentamethylbenzenemethanol; 1-Hydroxymethyl-2,3,4,5,6-pentamethylbenzene; PMBA
EINECS	207-613-6

Quality Control

Our 2,3,4,5,6-Pentamethylbenzyl Alcohol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	95 - 105 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.