Description

Bergapten is a naturally occurring furanocoumarin compound, also known as 5-methoxypsoralen. This bioactive molecule is valued for its specific photobiological activity and serves as a key reference standard and intermediate in research and development. It is primarily utilized in the pharmaceutical, cosmetic, and life science research sectors. Bergapten CAS NO 484-20-8 is supplied to meet the stringent quality requirements of industrial and laboratory applications.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Cosmetic & Dermatology Research: Investigated for its role in photochemotherapy (PUVA therapy) and as a component in studies related to skin sensitization and phototoxicity.
• Natural Product & Nutraceutical Analysis: Serves as a marker compound for the identification and quantification of furanocoumarins in botanical extracts, herbal medicines, and food products like bergamot oil.
• Biochemical Research: Employed in studies of cytochrome P450 enzyme interactions, DNA cross-linking mechanisms, and cellular response to UVA light.
• Agricultural Chemistry: Studied for its natural pesticidal and antifungal properties in plant defense mechanisms.

Basic Information

Product Name	Bergapten
CAS No.	484-20-8
Molecular Formula	C12H8O4
Molecular Weight	216.19 g/mol
Synonyms	5-Methoxypsoralen; 5-MOP; Heraclin; Majudin; Bergaptene; 4-Methoxy-7H-furo[3,2-g]chromen-7-one; 5-Methoxy-2H-furo[3,2-g]chromen-2-one
EINECS	207-604-5

Quality Control

Our Bergapten is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by spectroscopic methods (IR, NMR). We provide Certificates of Analysis (COA) with detailed batch-specific data, ensuring traceability and compliance with research and industrial standards. Custom purity grades, including analytical and pharmaceutical reference standards, are available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	188°C - 192°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.