Description

3-Mercaptoindole is a versatile sulfur-containing heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an indole ring and a reactive thiol group, makes it an invaluable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of tryptamine derivatives, melatonin analogs, and other bioactive indole alkaloids.
• Agrochemical Research: Used in developing novel fungicides and plant growth regulators that leverage the indole-thiol moiety.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers and conductive materials.
• Chemical Synthesis: Serves as a versatile nucleophile and ligand in metal-catalyzed coupling reactions and asymmetric synthesis.
• Bioconjugation Chemistry: Utilized for site-specific protein and peptide labeling via thiol-reactive chemistry.
• Research & Development: Fundamental reagent in academic and industrial R&D for exploring new heterocyclic chemistry and drug discovery pathways.

Basic Information

Product Name	3-Mercaptoindole
CAS No.	480-94-4
Molecular Formula	C8H7NS
Molecular Weight	149.21 g/mol
Synonyms	3-Indolethiol; 1H-Indole-3-thiol; Indole-3-thiol; 3-Thioindoxyl; 3-Sulfanylindole; 3-Mercapto-1H-indole; 480-94-4; NSC 403697
EINECS	207-560-7

Quality Control

Our 3-Mercaptoindole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The material is easily oxidized; prolonged exposure to air or elevated temperatures should be avoided. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.