Description

Diprophylline CAS NO 479-18-5 is a xanthine derivative and a bronchodilator belonging to the methylxanthine class of pharmaceutical compounds. It is valued for its therapeutic action in relaxing bronchial smooth muscle and stimulating the respiratory center. This active pharmaceutical ingredient (API) is essential for manufacturers in the pharmaceutical industry, particularly for formulating respiratory medications to treat conditions such as asthma, chronic bronchitis, and other obstructive airway diseases.

Application

• Pharmaceutical API: Primary use as the active ingredient in bronchodilator formulations for asthma and chronic obstructive pulmonary disease (COPD).
• Respiratory Therapeutics: Formulated into tablets, capsules, and injectable solutions for the treatment of bronchospasm.
• Veterinary Medicine: Used in veterinary pharmaceuticals for the management of respiratory distress in animals.
• Research & Development: Serves as a reference standard and a key intermediate in pharmacological research and new drug development.
• Combination Therapies: Can be combined with other agents like expectorants in compound cough and cold preparations.

Basic Information

Product Name	Diprophylline
CAS No.	479-18-5
Molecular Formula	C10H14N4O4
Molecular Weight	254.24 g/mol
Synonyms	Dyphylline; Dihydroxypropyltheophylline; 7-(2,3-Dihydroxypropyl)-1,3-dimethylpurine-2,6-dione; 1,3-Dimethyl-7-(2,3-dihydroxypropyl)xanthine; Glyphylline; Neothylline; Protophylline; Silbephylline; Solufyllin; Theophylline, 7-(2,3-dihydroxypropyl)-1,3-dimethyl-
EINECS	207-525-8

Quality Control

Our Diprophylline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide full traceability and support our customers with detailed Certificates of Analysis (COA) that confirm identity, purity, and impurity profiles. Specifications are designed to align with major pharmacopoeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.