Description

(E/Z)-1-Bromo-2-Fluoroethylene CAS NO 460-11-7 is a versatile halogenated olefin building block, prized for its unique reactivity profile that enables the introduction of both bromine and fluorine functionalities in a single step. This compound is essential for advanced organic synthesis, particularly in the development of novel fluorinated molecules with tailored properties. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to create compounds with enhanced bioactivity, stability, or specific physical characteristics.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and novel drug candidates, leveraging the fluorine atom's ability to modulate metabolism and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the fluorine moiety enhances biological activity and environmental stability.
• Fluorinated Polymer & Material Science: Serves as a monomer or precursor for creating specialty polymers, liquid crystals, and electronic materials with unique dielectric, surface, or optical properties.
• Organic Synthesis Reagent: A valuable reagent in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to construct complex molecular architectures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and developing fluorinated compounds for various high-tech applications.

Basic Information

Product Name	(E/Z)-1-Bromo-2-Fluoroethylene
CAS No.	460-11-7
Molecular Formula	C2H2BrF
Molecular Weight	124.94 g/mol
Synonyms	1-Bromo-2-fluoroethene; 1-Bromo-2-fluoroethylene; Bromofluoroethylene; Vinyl bromide, 2-fluoro-; 2-Fluoro-1-bromoethylene; 2-Fluorovinyl bromide; (E)-1-Bromo-2-fluoroethylene; (Z)-1-Bromo-2-fluoroethylene
EINECS	207-310-8

Quality Control

We maintain stringent quality control protocols for our (E/Z)-1-Bromo-2-Fluoroethylene, ensuring batch-to-batch consistency and high purity. Our standard analytical methods include Gas Chromatography (GC), NMR, and IR spectroscopy to verify identity and quantify isomeric composition and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We operate under a cGMP-compliant quality management system to meet the exacting standards of our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area, away from heat sources and incompatible materials. For long-term stability, storage under an inert atmosphere (e.g., nitrogen or argon) in a freezer (e.g., -20°C) is recommended. Keep away from strong bases and reactive metals.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0% (Total of E- and Z- isomers)
Isomeric Ratio (E/Z)	Specified upon request
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.