Description

4-Fluoro-6-(1H)Indazole Carboxylic Acid is a high-value fluorinated indazole derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a carboxylic acid and a fluorine-substituted indazole core, makes it indispensable for constructing complex molecules with targeted biological activity. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom enhances bioavailability and stability.
• Chemical Biology Probe Development: Employed in the synthesis of molecular probes for studying enzyme function and cellular pathways.
• Material Science Research: Acts as a precursor for specialty polymers and advanced organic materials requiring specific fluorinated heterocycles.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and custom synthesis projects.

Basic Information

Product Name	4-Fluoro-6-(1H)Indazole Carboxylic Acid
CAS No.	447-44-9
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	6-Fluoro-1H-indazole-4-carboxylic acid; 4-Fluoro-1H-indazole-6-carboxylic acid; 4-Fluoro-6-carboxyindazole; 1H-Indazole-6-carboxylic acid, 4-fluoro-; 447-44-9; 4-Fluoro-6-indazolecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-6-(1H)Indazole Carboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide full traceability and guarantee consistency to support your regulatory filings. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as per agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.