Description

(Z)-1-Chloro-2-Fluoroprop-1-Ene is a halogenated alkene building block of significant interest in advanced organic synthesis. Its value lies in its unique stereochemistry and reactivity, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and fluorinated materials with unique properties.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated components for electronic display and lighting technologies.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed reactions, such as Heck or Suzuki couplings, to introduce functionalized propene units.
• Organofluorine Chemistry: A valuable substrate for studying and developing new fluorination methodologies and reaction mechanisms.

Basic Information

Product Name	(Z)-1-Chloro-2-Fluoroprop-1-Ene
CAS No.	430-48-8
Molecular Formula	C3H4ClF
Molecular Weight	94.51 g/mol
Synonyms	(Z)-1-Chloro-2-fluoropropene; (Z)-2-Fluoro-1-chloropropene; (Z)-1-Chloro-2-fluoroprop-1-ene; (Z)-1-Chloro-2-fluoropropylene; (Z)-3-Chloro-2-fluoropropene; cis-1-Chloro-2-fluoropropene; (Z)-CF3CH=CHCl (isomer specific); 1-Chloro-2-fluoropropene (Z-isomer)
EINECS	207-076-5

Quality Control

Our (Z)-1-Chloro-2-Fluoroprop-1-Ene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, NMR, and chiral HPLC analysis, to ensure high chemical and isomeric purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, ideally at 2-8°C (refrigerated) to minimize volatility and degradation. Due to its highly volatile nature, keep away from heat, sparks, and open flame. Containers should be kept upright and securely sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Isomeric Purity (Z-isomer, GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.