

share
2-Bromo-1-Chloro-1,1-Difluoro-Ethane CAS NO 421-01-2
Unit Price:
CAS No.:421-01-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Bromo-1-Chloro-1,1-Difluoro-Ethane is a halogenated hydrocarbon building block valued for its unique reactivity profile, making it a versatile intermediate in advanced chemical synthesis. This compound is essential for introducing difluoromethylene and halogenated ethyl moieties into target molecules, enabling the development of novel materials and active ingredients. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise fluorination and functionalization.
Application
- Pharmaceutical Intermediate: A key synthon in the development of fluorinated active pharmaceutical ingredients (APIs), where the difluoro group can enhance metabolic stability and bioavailability.
- Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogen atoms for structural diversification.
- Refrigerant & Propellant Formulation: Serves as a precursor or component in the manufacturing of specialty fluorocarbon blends for cooling and propulsion systems.
- Polymer & Material Science: Acts as a monomer or modifying agent in the synthesis of fluorinated polymers, coatings, and elastomers with enhanced chemical and thermal resistance.
- Organic Synthesis Reagent: Employed in laboratories for introducing bromo, chloro, and difluoro functional groups in complex molecule construction, including nucleophilic substitution and coupling reactions.
- Fire Extinguishing Agent Precursor: Utilized in the development of next-generation, environmentally regulated halon replacements for fire suppression systems.
Basic Information
| Item | Detail |
|---|---|
| Product Name | 2-Bromo-1-Chloro-1,1-Difluoro-Ethane |
| CAS No. | 421-01-2 |
| Molecular Formula | C2H2BrClF2 |
| Molecular Weight | 179.39 g/mol |
| Synonyms | 1-Bromo-2-Chloro-1,1-Difluoroethane; 2-Bromo-1-Chloro-1,1-Difluoroethane; Halon 1211B1; BCF; 1,1-Difluoro-1-bromo-2-chloroethane; FC-12B1; R-12B1; Freon 12B1 |
| EINECS | Contact for details |
Quality Control
Our 2-Bromo-1-Chloro-1,1-Difluoro-Ethane is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing including GC, NMR, and Karl Fischer titration to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided and available upon request to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended storage temperature is 2-25°C.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Identification (IR) | Conforms to reference spectrum |
| Assay (GC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.1% |
| Density (at 20°C) | ~1.8 g/mL |
| Boiling Point | ~40-45°C |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
Hot Related Products


1,8-Diiodooctane CAS NO 24772-63-2


1-Butene, 3-Bromo-3-Methyl- CAS NO 865-58-7


1-(1-Bromovinyl)-4-Chlorobenzene, 90% CAS NO 89619-10-3


(Bromomethyl)Cyclopropane CAS NO 7051-34-5


Iodoform CAS NO 75-47-8


Methyl Iodide CAS NO 74-88-4


Bromoethane CAS NO 74-96-4


Ethyl Iodide CAS NO 75-03-6


Diiodomethane CAS NO 75-11-6


2-Bromoethyldimethylamine CAS NO 5459-68-7


1-Bromopinacolone CAS NO 5469-26-1


9-Chloro-1-Nonanol CAS NO 51308-99-7


2-Bromoethyl Ethyl Ether CAS NO 592-55-2


1-Bromo-3-Fluoropropane CAS NO 352-91-0


(E)-1-Chlorobut-2-Ene CAS NO 4894-61-5


1,2-Dibromo-1-Ethoxyethane CAS NO 2983-26-8


1,1,3,3-Tetrabromoacetone CAS NO 22612-89-1


1-Bromopropane CAS NO 106-94-5


2-Bromopentane CAS NO 107-81-3


4-Nitrobenzyl Bromide CAS NO 100-11-8
Why choose US
Trusted Manufacturer
With our own production facilities, we ensure consistent quality, reliable supply, and full traceability.
Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.





