Description

2-Fluorothiophene is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its unique reactivity, where the fluorine substituent and the electron-rich thiophene ring enable precise modifications in complex molecular architectures. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional materials.

Application

• Key synthetic intermediate in the development of pharmaceutical candidates, particularly for central nervous system (CNS) and oncology targets.
• Building block for agrochemicals, such as herbicides and fungicides, where the fluorine atom enhances biological activity and stability.
• Precursor in the synthesis of functional polymers and organic electronic materials (e.g., OLEDs, semiconductors) due to its conjugated system.
• Used in ligand design for catalysis and in the preparation of complex fluorinated molecules for material science applications.
• Intermediate for dyes and pigments research, leveraging its heterocyclic structure.

Basic Information

Product Name	2-Fluorothiophene
CAS No.	400-13-5
Molecular Formula	C4H3FS
Molecular Weight	102.13 g/mol
Synonyms	2-Fluorothiophene; Thiophene, 2-fluoro-; α-Fluorothiophene; 2-Fluoro-thiophene; 2-Thienyl fluoride; 2-Fluorothiofuran; 2-FT
EINECS	206-906-9

Quality Control

Our 2-Fluorothiophene is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.