Description

Methyl 4-Iodoisothiazole-3-Carboxylate is a high-value, halogenated heterocyclic building block essential for advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the isothiazole core's bioactivity.
• Material Science: Serves as a precursor for functionalized polymers or ligands used in catalysis and advanced materials.
• Chemical Synthesis: The iodine and ester functional groups make it a versatile substrate for cross-coupling reactions (e.g., Suzuki, Sonogashira) and further derivatization.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	Methyl 4-Iodoisothiazole-3-Carboxylate
CAS No.	397329-61-2
Molecular Formula	C5H4INO2S
Molecular Weight	268.06 g/mol
Synonyms	Methyl 4-iodo-1,2-thiazole-3-carboxylate; 3-Carbomethoxy-4-iodoisothiazole; 4-Iodoisothiazole-3-carboxylic acid methyl ester; Methyl 4-iodoisothiazole-3-carboxylate; 397329-61-2; 4-Iodo-3-isothiazolecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Iodoisothiazole-3-Carboxylate undergoes rigorous quality testing to ensure compliance with industry standards for research and development chemicals. We employ advanced analytical techniques including HPLC, NMR, and MS to verify identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.