Description

Ethyl 2-(4-Methoxybenzamido)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for developing next-generation drug candidates, leveraging its unique fused ring system to modulate biological activity and pharmacokinetic properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of proprietary drug candidates, especially those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities within the tetrahydrocycloheptathiophene class.
• Contract Research Organization (CRO) & CDMO Services: Supplied to organizations engaged in custom synthesis and process development for client-sponsored drug discovery programs.
• Academic Research: Utilized in university and institutional labs for fundamental research on heterocyclic chemistry and the development of new synthetic methodologies.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	Ethyl 2-(4-Methoxybenzamido)-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxylate
CAS No.	397290-59-4
Molecular Formula	C22H25NO4S
Molecular Weight	399.50 g/mol
Synonyms	Ethyl 2-[(4-methoxybenzoyl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate; 2-(4-Methoxybenzamido)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic Acid Ethyl Ester; 397290-59-4; UNII-9V8T6C6B4F; 9V8T6C6B4F; SCHEMBL233468; AKOS040759623; ZINC19764295
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Methoxybenzamido)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.