Description

Bicyclo[3.1.0]Hex-3-En-2-One, 4,5,6,6-Tetramethyl-, (-)- (9Ci) is a high-purity, chiral bicyclic ketone building block of significant interest in advanced organic synthesis. Its unique sterically hindered and strained structure makes it a valuable precursor for synthesizing complex molecules with specific three-dimensional architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where its bicyclic framework contributes to unique biological activity and selectivity.
• Flavor & Fragrance Chemistry: Acts as a precursor for synthesizing complex terpenoid-like aroma molecules and high-value odorants due to its camphoraceous structural motif.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials that require rigid, functionalized monomer units.
• Asymmetric Catalysis Ligand Precursor: Provides a scaffold for developing novel chiral ligands and organocatalysts used in enantioselective synthesis.
• Academic & Industrial R&D: A valuable tool compound for methodological studies in organic chemistry, including cycloaddition reactions and strain-release functionalization.

Basic Information

Product Name	Bicyclo[3.1.0]Hex-3-En-2-One, 4,5,6,6-Tetramethyl-, (-)- (9Ci)
CAS No.	396665-47-7
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(-)-4,5,6,6-Tetramethylbicyclo[3.1.0]hex-3-en-2-one; (1S,5S)-4,5,6,6-Tetramethylbicyclo[3.1.0]hex-3-en-2-one; 4,5,6,6-Tetramethylbicyclo[3.1.0]hex-3-en-2-one, (-)-; Tetramethylbicyclohexenone; Bicyclo[3.1.0]hex-3-en-2-one, 4,5,6,6-tetramethyl-, (1S,5S)-; L-(-)-4,5,6,6-Tetramethyl-3-bicyclo[3.1.0]hexen-2-one
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.0]Hex-3-En-2-One, 4,5,6,6-Tetramethyl-, (-)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.