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R-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Diphenyl-[1,1'-Binaphthalene]-2,2'-Diol CAS NO 396134-73-9


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CAS No.:396134-73-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

R-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Diphenyl-[1,1'-Binaphthalene]-2,2'-Diol is a sophisticated chiral ligand and building block of significant interest in advanced organic synthesis. Its value lies in its rigid, three-dimensional structure, which is highly effective for inducing enantioselectivity in catalytic reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries who require high-purity chiral auxiliaries for asymmetric synthesis and catalyst development.

Application

  • As a chiral ligand in asymmetric metal-catalyzed reactions, including hydrogenation, Diels-Alder, and aldol additions.
  • As a key building block for the synthesis of more complex, functionalized BINOL (1,1'-Bi-2-naphthol) derivatives.
  • In the research and development of novel organocatalysts for enantioselective transformations.
  • For the preparation of chiral molecular recognition systems and sensors.
  • In the synthesis of advanced pharmaceutical intermediates where precise stereochemical control is critical.
  • As a precursor for chiral polymers and materials with specific optical properties.

Basic Information

Product Name R-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Diphenyl-[1,1'-Binaphthalene]-2,2'-Diol
CAS No. 396134-73-9
Molecular Formula C32H30O2
Molecular Weight 446.58 g/mol
Synonyms (R)-H8-BINOL-Diphenyl; (R)-Octahydro-3,3'-diphenyl-1,1'-binaphthalene-2,2'-diol; (R)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-diphenyl-2,2'-dihydroxy-1,1'-binaphthyl; (R)-H8-3,3'-Diphenyl-BINOL; R-H8-Diphenyl-BINOL; (R)-3,3'-Diphenyl-H8-BINOL; (R)-Perhydro-3,3'-diphenyl-[1,1'-binaphthalene]-2,2'-diol
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Quality Control

Our production of this advanced chiral chemical adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Every lot is characterized by modern analytical techniques, including HPLC, chiral HPLC, and 1H/13C NMR, to confirm identity, chemical purity, and enantiomeric excess (ee). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged manipulations.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0% ee
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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