Description

7-Bromo-5-Fluoro-1H-Indole-2-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its unique halogenated indole scaffold, which serves as a critical precursor for developing novel pharmacologically active compounds. This intermediate is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating targeted molecules with specific biological or physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, neurology, and anti-infective therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as OLEDs and conductive polymers, due to the indole core's electron-rich properties.
• Chemical Biology Probe Development: Employed in creating fluorescent tags, enzyme inhibitors, and other molecular probes for diagnostic and research applications.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for method development and exploratory chemistry projects.

Basic Information

Product Name	7-Bromo-5-Fluoro-1H-Indole-2-Carboxylic Acid Ethyl Ester
CAS No.	396076-60-1
Molecular Formula	C11H9BrFNO2
Molecular Weight	286.10 g/mol
Synonyms	Ethyl 7-Bromo-5-fluoro-1H-indole-2-carboxylate; 7-Bromo-5-fluoroindole-2-carboxylic acid ethyl ester; 1H-Indole-2-carboxylic acid, 7-bromo-5-fluoro-, ethyl ester; 396076-60-1; 7-Br-5-F-1H-Indole-2-COOEt; 5-Fluoro-7-bromoindole-2-carboxylic acid ethyl ester; Ethyl 5-fluoro-7-bromo-1H-indole-2-carboxylate
EINECS	Contact for details

Quality Control

Our 7-Bromo-5-Fluoro-1H-Indole-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.