Description

Ethyl 6-Bromo-4-Fluoro-1H-Indole-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a versatile scaffold for further functionalization. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, particularly for oncology and central nervous system (CNS) targets.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the research and development of advanced organic electronic materials and functional dyes.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in academic and CRO laboratories.
• Chemical Synthesis: Enables the construction of complex molecular architectures through cross-coupling reactions and other transformations.

Basic Information

Product Name	Ethyl 6-Bromo-4-Fluoro-1H-Indole-2-Carboxylate
CAS No.	396075-55-1
Molecular Formula	C11H9BrFNO2
Molecular Weight	286.10 g/mol
Synonyms	6-Bromo-4-fluoro-1H-indole-2-carboxylic acid ethyl ester; Ethyl 6-bromo-4-fluoroindole-2-carboxylate; 1H-Indole-2-carboxylic acid, 6-bromo-4-fluoro-, ethyl ester; 396075-55-1; 6-Bromo-4-fluoroindole-2-carboxylic acid ethyl ester; 4-Fluoro-6-bromo-1H-indole-2-carboxylic acid ethyl ester; Ethyl 4-fluoro-6-bromo-1H-indole-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromo-4-Fluoro-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.