Description

2-Thiophenecarboxylic Acid, 4,5-Dibromo-3-Fluoro-, Methyl Ester is a high-value, multi-substituted heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring precise molecular modifications to develop novel materials and active compounds. It is primarily utilized in the pharmaceutical and agrochemical sectors for the synthesis of complex molecules, where its specific halogenated thiophene scaffold introduces unique electronic and steric properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the thiophene core for bioactivity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials, such as semiconductors and OLED components.
• Chemical Synthesis: Employed as a versatile building block in organic synthesis for coupling reactions (e.g., Suzuki, Stille) and to introduce fluorinated, brominated motifs into target molecules.
• Ligand and Catalyst Development: Useful for constructing complex ligands for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Thiophenecarboxylic Acid, 4,5-Dibromo-3-Fluoro-, Methyl Ester
CAS No.	395664-58-1
Molecular Formula	C7H3Br2FO2S
Molecular Weight	321.97 g/mol
Synonyms	Methyl 4,5-dibromo-3-fluorothiophene-2-carboxylate; 4,5-Dibromo-3-fluoro-2-thiophenecarboxylic acid methyl ester; 3-Fluoro-4,5-dibromothiophene-2-carboxylic acid methyl ester; Methyl 3-fluoro-4,5-dibromothiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 4,5-dibromo-3-fluoro-, methyl ester; 4,5-Dibromo-3-fluorothiophene-2-methyl carboxylate
EINECS	Contact for details

Quality Control

Every batch of 2-Thiophenecarboxylic Acid, 4,5-Dibromo-3-Fluoro-, Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (NMR, IR), and impurity profile is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.