Description

3-Bromo-5-Nitro-1-(Oxan-2-Yl)-1H-Indazole is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Organic Synthesis Reagent: Serves as a versatile precursor for further functionalization, enabling the creation of diverse indazole-based compound libraries.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents and pesticides.
• Material Science Research: Investigated as a precursor for specialty polymers or organic electronic materials due to its fused aromatic system.

Basic Information

Product Name	3-Bromo-5-Nitro-1-(Oxan-2-Yl)-1H-Indazole
CAS No.	395099-73-7
Molecular Formula	C₁₂H₁₂BrN₃O₃
Molecular Weight	326.15 g/mol
Synonyms	3-Bromo-5-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole; 1H-Indazole, 3-bromo-5-nitro-1-(tetrahydro-2H-pyran-2-yl)-; 3-Bromo-5-nitro-1-(tetrahydropyran-2-yl)-1H-indazole; 1-(Oxan-2-yl)-3-bromo-5-nitro-1H-indazole; 395099-73-7; 3-Bromo-5-nitro-1-(2-tetrahydropyranyl)-1H-indazole; 3-Bromo-5-nitro-1-(THP)-1H-indazole
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Nitro-1-(Oxan-2-Yl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider maintaining the product under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.