Description

3-(3-(Trifluoromethyl)Phenyl)-5-Nitro-1H-Indazole is a high-purity, advanced pharmaceutical intermediate characterized by its unique indazole core and trifluoromethylphenyl substitution. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, especially for projects involving kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly kinase inhibitors.
• Chemical Research & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Research: Serves as a precursor in the development of new crop protection agents and pesticides.
• Material Science: Investigated for the synthesis of specialty polymers and advanced organic materials with specific electronic properties.
• Academic Research: Utilized in universities and laboratories for studying heterocyclic chemistry and fluorinated compound reactions.

Basic Information

Product Name	3-(3-(Trifluoromethyl)Phenyl)-5-Nitro-1H-Indazole
CAS No.	395099-31-7
Molecular Formula	C14H8F3N3O2
Molecular Weight	307.23 g/mol
Synonyms	5-Nitro-3-[3-(trifluoromethyl)phenyl]-1H-indazole; 3-(3-(Trifluoromethyl)phenyl)-5-nitro-1H-indazole; 1H-Indazole, 3-[3-(trifluoromethyl)phenyl]-5-nitro-; 395099-31-7; 3-(3-Trifluoromethylphenyl)-5-nitroindazole; 5-Nitro-3-(3-trifluoromethylphenyl)indazole; 5-Nitro-3-(α,α,α-trifluoro-m-tolyl)indazole
EINECS	Contact for details

Quality Control

Our 3-(3-(Trifluoromethyl)Phenyl)-5-Nitro-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and tendency to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.