Description

n-Methoxy-n-Methyl-1H-Indole-6-Carboxamide is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the indole scaffold's bioactivity.
• Material Science: Serves as a building block for creating advanced organic electronic materials and functional polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical spaces.
• Peptidomimetics: The amide functionality makes it valuable for designing and synthesizing peptidomimetic compounds.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	n-Methoxy-n-Methyl-1H-Indole-6-Carboxamide
CAS No.	394653-94-2
Molecular Formula	C12H14N2O2
Molecular Weight	218.25 g/mol
Synonyms	N-Methoxy-N-methyl-1H-indole-6-carboxamide; 1H-Indole-6-carboxamide, N-methoxy-N-methyl-; N-Methoxy-N-methylindole-6-carboxamide; 6-(N-Methoxy-N-methylcarbamoyl)indole; Weinreb Amide of Indole-6-carboxylic Acid; Indole-6-carboxylic acid N-methoxy-N-methylamide; N-Methyl-N-methoxy-1H-indole-6-carboxamide; CAS 394653-94-2
EINECS	Contact for details

Quality Control

Our n-Methoxy-n-Methyl-1H-Indole-6-Carboxamide is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.