Description

1-(2-Thienylsulfonyl)-1H-Benzotriazole is a specialized heterocyclic sulfonamide compound that serves as a versatile building block in advanced organic synthesis. Its unique molecular architecture, featuring both benzotriazole and thienylsulfonyl moieties, makes it a valuable intermediate for constructing complex pharmacologically active molecules. This high-purity intermediate is primarily sought by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the benzotriazole core contributes to biological activity.
• Material Science Research: Employed as a precursor for synthesizing specialty polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology Probes: Serves as a scaffold for developing biochemical probes and diagnostic agents due to its ability to interact with biological targets.
• Academic & Industrial R&D: A critical reagent for method development and exploratory synthesis in organic chemistry laboratories worldwide.

Basic Information

Product Name	1-(2-Thienylsulfonyl)-1H-Benzotriazole
CAS No.	394245-72-8
Molecular Formula	C10H7N3O2S2
Molecular Weight	265.31 g/mol
Synonyms	1H-Benzotriazole, 1-(2-thienylsulfonyl)-; 1-(Thiophen-2-ylsulfonyl)-1H-benzotriazole; 1-(2-Thienylsulfonyl)benzotriazole; TSBt; 2-(1H-Benzotriazol-1-ylsulfonyl)thiophene; Benzotriazole-1-sulfonic acid thiophen-2-yl ester
EINECS	Contact for details

Quality Control

Our production of 1-(2-Thienylsulfonyl)-1H-Benzotriazole adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.