Description

2-(5-Bromo-7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in modern organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the discovery and scale-up of new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex drug molecules, especially those with indole-based scaffolds.
• Medicinal Chemistry Research: Used extensively in R&D for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: A key precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) or oncology targets.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Custom Synthesis: Provides a versatile starting point for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.

Basic Information

Product Name	2-(5-Bromo-7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic Acid
CAS No.	393509-23-4
Molecular Formula	C₁₃H₁₁BrFNO₂
Molecular Weight	312.14 g/mol
Synonyms	2-(5-Bromo-7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid; 5-Bromo-7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indole-3-acetic acid; 393509-23-4; 2-(5-Bromo-7-fluoro-2,3,4,9-tetrahydro-1H-cyclopenta[b]indol-3-yl)acetic acid; 5-Bromo-7-fluoro-2,3,4,9-tetrahydro-1H-cyclopenta[b]indole-3-acetic acid; (5-Bromo-7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid; 2-(5-Bromo-7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)ethanoic acid
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and full analytical data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.