Description

2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid is a high-purity fluorinated indole acetic acid derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in enabling the synthesis of novel, complex molecules with potential therapeutic applications, particularly in central nervous system (CNS) and oncology research. This compound is essential for medicinal chemistry research and development teams in the pharmaceutical and biotechnology sectors who require reliable, high-quality building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique fluorinated tetrahydrocyclopentaindole scaffold.
• Bioconjugation & Probe Development: The carboxylic acid functional group allows for conjugation to other molecules, useful in creating chemical probes for biological target identification.
• Preclinical Drug Development: Serves as a starting material for producing compounds required for in vitro and in vivo efficacy and safety testing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules for clients.

Basic Information

Product Name	2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic Acid
CAS No.	393509-22-3
Molecular Formula	C₁₃H₁₂FNO₂
Molecular Weight	233.24 g/mol
Synonyms	2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid; 7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indole-3-acetic acid; 393509-22-3; 2-(7-Fluoro-2,3,4,9-tetrahydro-1H-cyclopenta[b]indol-3-yl)acetic acid; 7-Fluoro-3-carboxymethyl-1,2,3,4-tetrahydrocyclopenta[b]indole; FTHCIA; 7-Fluoro-THCA
EINECS	Contact for details

Quality Control

Our production of 2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.