Description

Ethyl 2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities. The material is supplied with a focus on batch-to-batch consistency and reliable purity to support critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Integral in the development and optimization of synthetic routes for fluoro-substituted tetrahydrocyclopenta[b]indole-based active pharmaceutical ingredients.
• Contract Manufacturing: Supplied to CDMOs for the cGMP production of clinical trial materials and commercial APIs.
• Biochemical Research: May be utilized in the development of specialized probes or ligands for biological target studies.

Basic Information

Product Name	Ethyl 2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetate
CAS No.	393509-21-2
Molecular Formula	C15H16FNO2
Molecular Weight	261.29 g/mol
Synonyms	Ethyl (7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetate; 7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indole-3-acetic acid ethyl ester; 393509-21-2; 7-Fluoro-3-carbethoxymethyl-1,2,3,4-tetrahydrocyclopenta[b]indole; Ethyl 7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indole-3-acetate; 3-Carbethoxymethyl-7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indole
EINECS	Contact for details

Quality Control

Our Ethyl 2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring material suitable for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.