Description

R-4-Aminomethyl-Thiazolidine-3-Carboxylic Acid tert-Butyl Ester is a high-purity, protected amino acid derivative serving as a critical chiral building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise stereochemistry and functional group compatibility in complex molecule construction. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other sophisticated fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for complex small molecule drugs.
• Peptidomimetic Synthesis: Used to introduce constrained thiazolidine scaffolds into peptide backbones to enhance metabolic stability and bioavailability.
• API Development: Serves as a building block in the multi-step synthesis of candidate drug molecules, especially those targeting neurological and metabolic disorders.
• Chemical Biology Probes: Employed in the creation of specialized probes and ligands for studying enzyme mechanisms and receptor interactions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in stereoselective reactions to create enantiomerically pure compounds.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global pharmaceutical market.

Basic Information

Product Name	R-4-Aminomethyl-Thiazolidine-3-Carboxylic Acid tert-Butyl Ester
CAS No.	391248-13-8
Molecular Formula	C10H18N2O2S
Molecular Weight	230.33 g/mol
Synonyms	(R)-4-(Aminomethyl)thiazolidine-3-carboxylic acid tert-butyl ester; tert-Butyl (R)-4-(aminomethyl)thiazolidine-3-carboxylate; (R)-3-(tert-Butoxycarbonyl)-4-(aminomethyl)thiazolidine; (R)-Boc-4-Aminomethyl-thiazolidine-3-carboxylic acid; (R)-4-Aminomethyl-thiazolidine-3-carboxylic acid t-butyl ester; (R)-4-Aminomethyl-thiazolidine-3-carboxylic acid O-tert-butyl ester; (R)-N-Boc-4-aminomethylthiazolidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our R-4-Aminomethyl-Thiazolidine-3-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and cGMP manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider using desiccants and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.