Description

4-(4-Chlorophenyl)Thiophene-2-Carboxylic Acid is a high-purity organic building block of significant importance in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the bioactivity of the thiophene-chlorophenyl scaffold.
• Material Science Research: Serves as a monomer or building block for creating conjugated polymers and organic semiconductors for electronic applications.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-organic catalysis and coordination chemistry.
• Chemical Research & Development: A versatile starting material for academic and industrial research into heterocyclic and biaryl compound libraries.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific custom synthesis projects.

Basic Information

Product Name	4-(4-Chlorophenyl)Thiophene-2-Carboxylic Acid
CAS No.	386715-46-4
Molecular Formula	C11H7ClO2S
Molecular Weight	238.69 g/mol
Synonyms	2-Thiophenecarboxylic acid, 4-(4-chlorophenyl)-; 4-(p-Chlorophenyl)thiophene-2-carboxylic acid; 4-(4-Chlorophenyl)-2-thiophenecarboxylic acid; 4-(4-Chlorophenyl)thiophene-2-carboxylate; 4-(4'-Chlorophenyl)thiophene-2-carboxylic acid; 386715-46-4; AKOS BRN 0972; CTK8G0338
EINECS	Contact for details

Quality Control

Our production of 4-(4-Chlorophenyl)Thiophene-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.