Description

7-Hydroxy-4-(3-Trifluoromethylphenyl)Coumarin is a specialized fluorinated coumarin derivative that serves as a high-value synthetic intermediate and functional material. Its core value lies in the unique photophysical properties imparted by the coumarin scaffold and the electron-withdrawing trifluoromethyl group, making it a critical building block for advanced applications. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional dyes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Fluorescent Probe & Sensor Development: Serves as a core structure for creating sensitive fluorescent probes used in bioimaging, chemical sensing, and diagnostic assays.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a building block for electron-transport materials and emissive layers in display and lighting technologies.
• Photoinitiator & Photopolymerization: Utilized in formulations for UV-curable inks, coatings, and adhesives due to its light-absorbing characteristics.
• Academic & R&D Reference Standard: Essential compound for chemical research, method development, and spectroscopic studies in university and corporate laboratories.

Basic Information

Product Name	7-Hydroxy-4-(3-Trifluoromethylphenyl)Coumarin
CAS No.	386704-09-2
Molecular Formula	C₁₆H₉F₃O₃
Molecular Weight	306.24 g/mol
Synonyms	7-Hydroxy-4-[3-(trifluoromethyl)phenyl]-2H-chromen-2-one; 4-(3-Trifluoromethylphenyl)-7-hydroxycoumarin; 7-Hydroxy-4-(3-trifluoromethylphenyl)-2H-1-benzopyran-2-one; 7-Hydroxy-4-(α,α,α-trifluoro-m-tolyl)coumarin; 2H-1-Benzopyran-2-one, 7-hydroxy-4-[3-(trifluoromethyl)phenyl]-; 7-Hydroxy-4-(m-trifluoromethylphenyl)coumarin
EINECS	Contact for details

Quality Control

Our 7-Hydroxy-4-(3-Trifluoromethylphenyl)Coumarin is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with exacting R&D and production standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.