Description

5-Thiazoleacetic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific thiazole-acetic acid ester structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug molecules, particularly those targeting infectious diseases or metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the thiazole moiety contributes to biological activity.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for creating complex heterocyclic compounds in academic and industrial R&D settings.
• Peptide Mimetics & Bioconjugation: The protected amino acid ester functionality makes it suitable for constructing peptide analogs or for bioconjugation applications.
• Material Science: Potential use in the synthesis of specialty polymers or ligands for catalytic systems.

Basic Information

Product Name	5-Thiazoleacetic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Methyl Ester
CAS No.	385785-37-5
Molecular Formula	C11H16N2O4S
Molecular Weight	272.32 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-5-thiazoleacetic acid methyl ester; Methyl 2-[(tert-butoxycarbonyl)amino]-1,3-thiazole-5-acetate; Boc-5-Thiazoleglycine methyl ester; 2-(Boc-amino)thiazole-5-acetic acid methyl ester; tert-Butyl (5-(2-methoxy-2-oxoethyl)thiazol-2-yl)carbamate; 5-Thiazoleglycine, N-Boc-, methyl ester; CAS 385785-37-5
EINECS	Contact for details

Quality Control

Our production of 5-Thiazoleacetic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Methyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We support cGMP compliance for pharmaceutical applications and can provide material suitable for advanced research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.