Description

(2-Pyridyl)Dithiobimane is a specialized heterocyclic organic compound featuring a reactive dithiobimane moiety linked to a pyridine ring. This unique structure makes it a valuable reagent for bioconjugation and fluorescent labeling applications, particularly for tagging thiol groups in proteins and peptides. It is primarily utilized by researchers and manufacturers in the fields of biochemistry, proteomics, and pharmaceutical development for creating stable, fluorescently labeled biomolecules.

Application

• Fluorescent Probe Synthesis: Acts as a key intermediate for developing sensitive fluorescent probes targeting cysteine residues in proteins.
• Bioconjugation Chemistry: Used for the site-specific labeling of antibodies, enzymes, and other therapeutic proteins to create diagnostic or research tools.
• Proteomics Research: Enables the tagging and detection of thiol-containing peptides in mass spectrometry and gel-based analysis.
• Chemical Biology: Serves as a versatile building block for designing activity-based probes to study enzyme function and mechanism.
• Pharmaceutical Intermediate: Employed in the research and development stages of novel drug candidates that require targeted delivery or imaging capabilities.
• Material Science: Potential use in modifying surface properties of materials through thiol-reactive chemistry for biosensor development.

Basic Information

Product Name	(2-Pyridyl)Dithiobimane
CAS No.	385398-64-1
Molecular Formula	C₁₄H₁₀N₂S₂
Molecular Weight	270.37 g/mol
Synonyms	2-Pyridyldithiobimane; Py-2-DTB; 1,5-Diazabicyclo[3.3.0]octa-3,6-diene-2,8-dithione, 3,6-bis(2-pyridinyl)-; 3,6-Di(2-pyridyl)-1,5-diazabicyclo[3.3.0]octa-3,6-diene-2,8-dithione; (2-Pyridyl)dithiobimane; DTB-Py2
EINECS	Contact for details

Quality Control

Our (2-Pyridyl)Dithiobimane is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.