Description

2-(3-Chloropropyl)-3-(4-Methoxyphenyl)-1-Oxo-1,2,3,4-Tetrahydro-4-Isoquinolinecarboxylic Acid is a high-purity, synthetically valuable heterocyclic building block with the CAS registry number 385383-38-0. This compound is a critical intermediate in advanced pharmaceutical research and development, particularly for the synthesis of novel therapeutic agents targeting the central nervous system. It is essential for medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in neurological and psychiatric disorder research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel bioactive molecules.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, multi-functional heterocyclic compounds for various industrial applications.
• Academic Research: Used in universities and research institutes for studying synthetic methodologies and heterocyclic chemistry.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	2-(3-Chloropropyl)-3-(4-Methoxyphenyl)-1-Oxo-1,2,3,4-Tetrahydro-4-Isoquinolinecarboxylic Acid
CAS No.	385383-38-0
Molecular Formula	C20H20ClNO4
Molecular Weight	373.83 g/mol
Synonyms	4-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-(3-chloropropyl)-3-(4-methoxyphenyl)-1-oxo-; 1-Oxo-2-(3-chloropropyl)-3-(4-methoxyphenyl)-1,2,3,4-tetrahydro-4-isoquinolinecarboxylic acid; 385383-38-0; Tetrahydroisoquinoline carboxylic acid derivative; 3-(4-Methoxyphenyl)-2-(3-chloropropyl)-1-oxo-1,2,3,4-tetrahydro-4-isoquinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(3-Chloropropyl)-3-(4-Methoxyphenyl)-1-Oxo-1,2,3,4-Tetrahydro-4-Isoquinolinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.