Description

5-(3,5-Dimethoxyphenyl)-4-Phenyl-4H-1,2,4-Triazole-3-Thiol is a specialized heterocyclic compound belonging to the 1,2,4-triazole class, distinguished by its sulfur-containing thiol group and dimethoxyphenyl substituent. This molecular architecture makes it a valuable chemical building block and intermediate for advanced research and development in medicinal chemistry and material science. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or microbial infections.
• Agrochemical Research: Serves as a core structure for developing new fungicides, herbicides, or plant growth regulators due to its bioactive triazole-thiol moiety.
• Material Science: Used in the development of advanced polymers, ligands for metal-organic frameworks (MOFs), or corrosion inhibitors.
• Chemical Biology Probe: Employed in biochemical research as a tool compound to study enzyme inhibition or protein-ligand interactions.
• Coordination Chemistry: Acts as a versatile ligand for transition metals, forming complexes with potential catalytic or luminescent properties.

Basic Information

Item	Detail
Product Name	5-(3,5-Dimethoxyphenyl)-4-Phenyl-4H-1,2,4-Triazole-3-Thiol
CAS No.	385379-74-8
Molecular Formula	C₁₆H₁₅N₃O₂S
Molecular Weight	313.38 g/mol
Synonyms	5-(3,5-Dimethoxyphenyl)-4-phenyl-4H-1,2,4-triazole-3-thiol; 4-Phenyl-5-(3,5-dimethoxyphenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione; 385379-74-8; 3H-1,2,4-Triazole-3-thione, 4-phenyl-5-(3,5-dimethoxyphenyl)-2,4-dihydro-; 5-(3,5-Dimethoxy-phenyl)-4-phenyl-4H-[1,2,4]triazole-3-thiol
EINECS	Contact for details

Quality Control

Our 5-(3,5-Dimethoxyphenyl)-4-Phenyl-4H-1,2,4-Triazole-3-Thiol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to confirm identity and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure it meets your precise research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.