Description

1-[(5-Chlorothien-2-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic sulfonamide structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and other specialized therapeutic areas.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores with enhanced efficacy and selectivity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.
• Bioconjugation & Probe Development: Its functional groups make it suitable for creating labeled compounds and molecular probes for biochemical and diagnostic research.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents with novel modes of action.

Basic Information

Product Name	1-[(5-Chlorothien-2-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid
CAS No.	384847-77-2
Molecular Formula	C10H12ClNO4S2
Molecular Weight	309.79 g/mol
Synonyms	3-Piperidinecarboxylic acid, 1-[(5-chloro-2-thienyl)sulfonyl]-; 1-(5-Chlorothiophene-2-sulfonyl)piperidine-3-carboxylic acid; 5-Chloro-2-(3-carboxypiperidin-1-ylsulfonyl)thiophene; 384847-77-2; 1-(5-Chloro-2-thienylsulfonyl)piperidine-3-carboxylic acid; 1-(5-Chlorothiophen-2-ylsulfonyl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-[(5-Chlorothien-2-Yl)Sulfonyl]Piperidine-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured and tested in facilities that implement cGMP principles where applicable. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed on every batch. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.