Description

Ethyl 6-(tert-Butyl)-2-(2-(3,5-Dimethyl-4-Nitro-1H-Pyrazol-1-Yl)Acetamido)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical synthesis facilities engaged in cutting-edge drug discovery programs.

Application

This specialized intermediate serves as a key building block in sophisticated organic syntheses. Its primary applications include:

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents with improved efficacy and safety profiles.
• Heterocyclic Compound Synthesis: Serves as a core template for constructing complex molecules containing fused tetrahydrobenzo[b]thiophene and pyrazole rings.
• Agrochemical Research: Potential application in the development of new generation pesticides and herbicides, leveraging its unique bioactive scaffold.
• Academic & Institutional R&D: Employed in university and research institute laboratories for studies in advanced organic synthesis methodologies and new chemical entity (NCE) discovery.

Basic Information

Product Name	Ethyl 6-(tert-Butyl)-2-(2-(3,5-Dimethyl-4-Nitro-1H-Pyrazol-1-Yl)Acetamido)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate
CAS No.	384821-64-1
Molecular Formula	C22H30N4O5S
Molecular Weight	462.56 g/mol
Synonyms	Ethyl 6-tert-butyl-2-[[2-(3,5-dimethyl-4-nitro-1H-pyrazol-1-yl)acetyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 6-(tert-Butyl)-2-(2-(3,5-dimethyl-4-nitro-1H-pyrazol-1-yl)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ethyl ester; 4,5,6,7-Tetrahydro-6-(1,1-dimethylethyl)-2-[[[2-(3,5-dimethyl-4-nitro-1H-pyrazol-1-yl)acetyl]amino]benzo[b]thiophene-3-carboxylic acid, ethyl ester; CAS 384821-64-1; Tetrahydrobenzo[b]thiophene-3-carboxylate derivative
EINECS	Contact for details

Quality Control

Our production of Ethyl 6-(tert-Butyl)-2-(2-(3,5-Dimethyl-4-Nitro-1H-Pyrazol-1-Yl)Acetamido)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxylate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical R&D applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS). A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. Our quality management system is designed to support cGMP compliance for pharmaceutical development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.