Description

Ethyl 5-Acetoxy-1-Cyclopropyl-2-Methyl-1H-Indole-3-Carboxylate is a specialized indole derivative ester, serving as a crucial advanced pharmaceutical intermediate in modern synthetic chemistry. Its value lies in its functionalized indole core, which is a privileged scaffold for developing bioactive molecules targeting a range of therapeutic areas. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel drug candidates and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel indole-based drug candidates with potential activity in central nervous system (CNS) disorders, inflammation, and oncology.
• Organic Synthesis Reagent: Used in research-scale and process chemistry for constructing complex heterocyclic systems, leveraging the reactivity of its acetoxy and ester functional groups.
• Agrochemical Research: Intermediate in the development of new generation pesticides and herbicides that utilize modified indole structures for enhanced biological activity.
• Material Science Precursor: Potential starting material for synthesizing organic semiconductors or functional dyes due to the conjugated indole system.
• Academic & Contract Research: Valuable reference standard and synthetic tool for universities and CROs (Contract Research Organizations) conducting medicinal chemistry and methodological studies.

Basic Information

Product Name	Ethyl 5-Acetoxy-1-Cyclopropyl-2-Methyl-1H-Indole-3-Carboxylate
CAS No.	383402-59-3
Molecular Formula	C₁₇H₁₉NO₄
Molecular Weight	301.34 g/mol
Synonyms	5-Acetoxy-1-cyclopropyl-2-methyl-1H-indole-3-carboxylic acid ethyl ester; Ethyl 5-acetyloxy-1-cyclopropyl-2-methylindole-3-carboxylate; 1-Cyclopropyl-2-methyl-5-acetoxyindole-3-carboxylic acid ethyl ester; 383402-59-3; 1H-Indole-3-carboxylic acid, 5-(acetyloxy)-1-cyclopropyl-2-methyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Acetoxy-1-Cyclopropyl-2-Methyl-1H-Indole-3-Carboxylate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.