Description

7-Methyl-3-(Trideuteromethyl)Uric Acid is a high-purity, deuterated derivative of uric acid, specifically designed for advanced research and analytical applications. This compound is valued for its role as a stable isotope-labeled internal standard, enabling precise quantification and metabolic pathway tracing in complex biological matrices. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and clinical diagnostics sectors for method development and validation.

Application

• Stable Isotope-Labeled Internal Standard for the accurate quantification of uric acid and its metabolites in bioanalytical methods using LC-MS/MS.
• Metabolic Pathway Tracing in pharmacokinetic and drug metabolism studies to understand the biotransformation of purine-based compounds.
• Method Development & Validation in clinical research and diagnostic assay development for conditions related to purine metabolism, such as gout.
• Pharmaceutical Impurity Profiling and reference standard for quality control in the synthesis of related active pharmaceutical ingredients (APIs).
• Biomarker Research for investigating oxidative stress and metabolic disorders where uric acid is a key analyte.

Basic Information

Product Name	7-Methyl-3-(Trideuteromethyl)Uric Acid
CAS No.	383160-11-0
Molecular Formula	C7H5D3N4O3
Molecular Weight	199.17 g/mol
Synonyms	1,7-Dimethyluric Acid-d3; 3-(Trideuteromethyl)-7-methyluric Acid; 7-Methyl-1,3-dihydro-1,3-bis(methyl-d3)-2,6,8(7H)-purinetrione; 7-Methyl-3-(methyl-d3)uric Acid; Deuterated 1,7-Dimethyluric Acid; Uric Acid-d3 Derivative; 1,7-Dimethyl-2,6,8-trioxopurine-d3
EINECS	Contact for details

Quality Control

Our 7-Methyl-3-(Trideuteromethyl)Uric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and isotopic enrichment. Certificates of Analysis (COA) detailing identity, purity (typically ≥95% by HPLC), and deuterium incorporation are provided to guarantee consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Deuterium Incorporation	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.