Description

4-(2,6-Dimethyl-1H-Indol-3-Yl)-Thiazol-2-Ylamine is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole-thiazole hybrid structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially those targeting specific enzymatic pathways or receptor sites.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in the development of chemical probes for studying biological targets and signaling pathways in academic and industrial research.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex heterocyclic compounds with potential biological activity.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for the custom synthesis and scale-up of client-specific molecules for preclinical and clinical trials.

Basic Information

Product Name	4-(2,6-Dimethyl-1H-Indol-3-Yl)-Thiazol-2-Ylamine
CAS No.	382622-81-3
Molecular Formula	C₁₃H₁₃N₃S
Molecular Weight	243.33 g/mol
Synonyms	4-(2,6-Dimethyl-1H-indol-3-yl)-1,3-thiazol-2-amine; 2-Amino-4-(2,6-dimethyl-1H-indol-3-yl)thiazole; 4-(2,6-Dimethylindol-3-yl)thiazol-2-ylamine; 382622-81-3; 4-(2,6-Dimethyl-1H-indol-3-yl)-2-thiazolamine; 4-(2,6-Dimethyl-1H-indol-3-yl)thiazol-2-amine
EINECS	Contact for details

Quality Control

Our 4-(2,6-Dimethyl-1H-Indol-3-Yl)-Thiazol-2-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.