Description

2-(2-Nitrobenzamido)-n-((Tetrahydrofuran-2-Yl)Methyl)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxamide is a high-purity, complex heterocyclic organic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines nitrobenzamide, tetrahydrofuran, and tetrahydrobenzothiophene moieties, making it a versatile building block for constructing novel pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other specialized disease areas.

Application

This specialized chemical intermediate is designed for high-value research and development applications. Its primary uses include:

• Pharmaceutical Research & Development (R&D): Serving as a key synthetic precursor or scaffold in the discovery and optimization of new drug candidates.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to explore and modify biological activity profiles.
• Chemical Synthesis: Acting as a sophisticated building block for the synthesis of complex heterocyclic libraries for high-throughput screening.
• Academic Research: Used in university and institutional labs for studies in organic synthesis methodology and novel compound synthesis.
• Contract Research Organizations (CROs): Employed in custom synthesis projects and client-directed research for pharmaceutical clients.

Basic Information

Product Name	2-(2-Nitrobenzamido)-n-((Tetrahydrofuran-2-Yl)Methyl)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxamide
CAS No.	381680-10-0
Molecular Formula	C22H25N3O5S
Molecular Weight	443.52 g/mol
Synonyms	2-(2-Nitrobenzamido)-N-((tetrahydrofuran-2-yl)methyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide; 4,5,6,7-Tetrahydro-2-[[(2-nitrophenyl)carbonyl]amino]-N-[(tetrahydro-2-furanyl)methyl]benzo[b]thiophene-3-carboxamide; 381680-10-0; Tetrahydrobenzothiophene-3-carboxamide derivative; Advanced benzothiophene intermediate; Nitrobenzamide-thiophene conjugate.
EINECS	Contact for details

Quality Control

Our 2-(2-Nitrobenzamido)-n-((Tetrahydrofuran-2-Yl)Methyl)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxamide is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D applications. Each batch undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR/IR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture and contamination. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.