Description

7-tert-Butyl-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one is a high-purity, heterocyclic organic compound belonging to the fused thienopyrimidinone class, serving as a critical advanced intermediate in modern chemical synthesis. Its unique molecular architecture, featuring a benzo-fused thienopyrimidinone core with a tert-butyl substituent, makes it a valuable building block for constructing complex molecules with targeted biological or material properties. This compound is primarily sought by research institutions and pharmaceutical development companies engaged in medicinal chemistry, agrochemical research, and the development of novel functional materials.

Application

This specialized heterocyclic intermediate is designed for advanced research and development applications where precise molecular structure is paramount. Its primary uses include:

• Pharmaceutical Intermediate: Serving as a key scaffold or precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and other therapeutic areas.
• Agrochemical Research: Utilized in the development of new active ingredients for crop protection products, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acting as a building block for organic electronic materials, such as semiconductors or charge-transport layers, due to its conjugated system.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and tool compounds for studying biological pathways and protein function.
• Academic & Contract Research: Used in universities and CROs (Contract Research Organizations) for method development and exploratory synthesis projects.

Basic Information

Product Name	7-tert-Butyl-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one
CAS No.	380902-66-9
Molecular Formula	C15H18N2OS
Molecular Weight	274.38 g/mol
Synonyms	7-tert-Butyl-3,4,5,6-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one; 7-(tert-Butyl)-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one; 380902-66-9; Benzo[4,5]thieno[2,3-d]pyrimidin-4-one, 7-(1,1-dimethylethyl)-5,6,7,8-tetrahydro-3H-; 7-tert-Butyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our advanced intermediates. Production follows current Good Manufacturing Practices (cGMP) where applicable, and each batch is analyzed using validated methods including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and analytical data is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.