Description

Phosphonic Acid, [[5-(3-Fluorophenyl)-2-Pyridinyl]Methyl]-, Diethyl Ester is a specialized organophosphorus compound featuring a fluorinated bipyridyl structure, serving as a high-value chemical intermediate. Its molecular architecture is engineered to act as a key building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where precise functionalization is critical. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate unique fluorinated phosphonate motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies where the fluorophenyl-pyridinyl moiety is pharmacologically relevant.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and plant growth regulators, leveraging the bioactivity of the phosphonate ester group.
• Ligand and Catalyst Development: Serves as a sophisticated ligand precursor in organometallic chemistry and catalysis for asymmetric synthesis.
• Material Science Research: Employed in the creation of functionalized monomers for advanced polymers, metal-organic frameworks (MOFs), or surface-modifying agents.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Phosphonic Acid, [[5-(3-Fluorophenyl)-2-Pyridinyl]Methyl]-, Diethyl Ester
CAS No.	380894-77-9
Molecular Formula	C₁₇H₁₉FNO₃P
Molecular Weight	335.31 g/mol
Synonyms	Diethyl [[5-(3-fluorophenyl)-2-pyridinyl]methyl]phosphonate; [[5-(3-Fluorophenyl)-2-pyridinyl]methyl]phosphonic Acid Diethyl Ester; (5-(3-Fluorophenyl)pyridin-2-yl)methylphosphonic Acid Diethyl Ester; Diethyl (5-(3-Fluorophenyl)pyridin-2-yl)methylphosphonate; Phosphonic Acid, P-[[5-(3-Fluorophenyl)-2-pyridinyl]methyl]-, Diethyl Ester; 380894-77-9; (5-(3-Fluorophenyl)-2-pyridylmethyl)phosphonic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Every batch of Phosphonic Acid, [[5-(3-Fluorophenyl)-2-Pyridinyl]Methyl]-, Diethyl Ester is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.