Description

1H-Indole-1-Carboxylic Acid, 3-(1-Cyano-1-Methylethyl)-, 1,1-Dimethylethyl Ester is a high-purity, synthetically valuable indole derivative. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in organic synthesis. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides.
• Organic Synthesis Reagent: Serves as a versatile precursor for introducing the indole scaffold and cyano-functionalized side chains into more complex molecules.
• Material Science Research: Potential monomer or precursor for specialty polymers and advanced organic materials.
• Academic & Contract Research: Essential for medicinal chemistry programs and methodological studies in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 3-(1-Cyano-1-Methylethyl)-, 1,1-Dimethylethyl Ester
CAS No.	380626-46-0
Molecular Formula	C19H24N2O2
Molecular Weight	312.41 g/mol
Synonyms	tert-Butyl 3-(1-cyano-1-methylethyl)-1H-indole-1-carboxylate; 3-(2-Cyano-2-propanyl)-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-3-(1-cyano-1-methylethyl)indole; 3-(1-Cyano-1-methylethyl)-1H-indole-1-carboxylic acid tert-butyl ester; Boc-3-(1-cyano-1-methylethyl)indole; 380626-46-0; tert-Butyl 3-(2-cyano-2-propyl)indole-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-1-Carboxylic Acid, 3-(1-Cyano-1-Methylethyl)-, 1,1-Dimethylethyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.