Description

4-[5-(4-Ethoxy-3-Methoxybenzylidene)-4-Oxo-2-Thioxo-1,3-Thiazolidin-3-Yl]Butanoic Acid is a high-purity synthetic organic compound with a complex heterocyclic structure, serving as a critical advanced intermediate in pharmaceutical research and development. Its molecular architecture, featuring a rhodanine core with a butanoic acid side chain, makes it a valuable scaffold for designing novel bioactive molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing potential drug candidates and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting metabolic and inflammatory diseases.
• Rhodanine-based Library Synthesis: Essential precursor for creating diverse chemical libraries in medicinal chemistry for high-throughput screening and hit-to-lead optimization.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic bioactivity.
• Biochemical Probe Development: Serves as a core structure for designing molecular probes to study enzyme inhibition and biological pathways.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic & Contract Research: Supplied to university laboratories and CROs (Contract Research Organizations) for fundamental chemical research and custom synthesis projects.

Basic Information

Product Name	4-[5-(4-Ethoxy-3-Methoxybenzylidene)-4-Oxo-2-Thioxo-1,3-Thiazolidin-3-Yl]Butanoic Acid
CAS No.	380582-45-6
Molecular Formula	C₁₇H₁₉NO₅S₂
Molecular Weight	381.47 g/mol
Synonyms	4-[5-[(4-Ethoxy-3-methoxyphenyl)methylene]-4-oxo-2-thioxo-3-thiazolidinyl]butanoic acid; 3-[4-Carboxybutyl]-5-[(4-ethoxy-3-methoxyphenyl)methylene]-2-thioxo-4-thiazolidinone; Butanoic acid, 4-[5-[(4-ethoxy-3-methoxyphenyl)methylene]-4-oxo-2-thioxo-3-thiazolidinyl]-; 4-(5-((4-Ethoxy-3-methoxyphenyl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid; Rhodanine derivative CAS 380582-45-6; 4-(5-(4-Ethoxy-3-methoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)butyric acid
EINECS	Contact for details

Quality Control

Every batch of 4-[5-(4-Ethoxy-3-Methoxybenzylidene)-4-Oxo-2-Thioxo-1,3-Thiazolidin-3-Yl]Butanoic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.