Description

5-Chloro-3-Formyl-1H-Indole-2-Carboxylic Acid is a high-purity, multi-functional indole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its reactive formyl and carboxylic acid groups, which enable precise molecular construction and functionalization. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, particularly for oncology and central nervous system (CNS) targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing sophisticated heterocyclic libraries and novel chemical entities.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic electronic materials.
• Biochemical Probe Development: Serves as a starting material for creating fluorescent tags or molecular probes for biological imaging and assay development.

Basic Information

Product Name	5-Chloro-3-Formyl-1H-Indole-2-Carboxylic Acid
CAS No.	380448-07-7
Molecular Formula	C10H6ClNO3
Molecular Weight	223.61 g/mol
Synonyms	5-Chloro-3-formyl-1H-indole-2-carboxylic acid; 5-Chloro-2-carboxy-3-formylindole; 2-Carboxy-5-chloro-3-formylindole; 380448-07-7; 5-Chloro-3-formylindole-2-carboxylic acid; 1H-Indole-2-carboxylic acid, 5-chloro-3-formyl-; 5-Chloro-1H-indole-2-carboxylic acid, 3-formyl-
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Formyl-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.