Description

5-Bromo-7-Fluoro-1H-Indole-2,3-Dione is a high-purity, halogenated isatin derivative, a crucial building block in advanced organic synthesis. Its unique molecular structure, featuring both bromine and fluorine substituents, makes it a versatile intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, particularly those exploring kinase inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used as a precursor in the synthesis of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for creating specialized organic materials and functional dyes.
• Academic & R&D: Employed in university and industrial laboratories for methodological studies in heterocyclic and medicinal chemistry.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and biochemical tools.

Basic Information

Product Name	5-Bromo-7-Fluoro-1H-Indole-2,3-Dione
CAS No.	380431-78-7
Molecular Formula	C8H3BrFNO2
Molecular Weight	244.02 g/mol
Synonyms	5-Bromo-7-fluoroisatin; 7-Fluoro-5-bromo-1H-indole-2,3-dione; 5-Bromo-7-fluoroindoline-2,3-dione; 380431-78-7; 5-Bromo-7-fluoro-2,3-dihydro-1H-indole-2,3-dione; 7-Fluoro-5-bromoisatin; Isatin, 5-bromo-7-fluoro-
EINECS	Contact for details

Quality Control

Our 5-Bromo-7-Fluoro-1H-Indole-2,3-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.