Description

2-(2-Chloro-Acetylamino)-5-Phenyl-Thiophene-3-Carboxylic Acid Ethyl Ester is a high-value synthetic organic intermediate characterized by its thiophene core and functionalized amide and ester groups. This compound is critical for facilitating complex molecular transformations in advanced pharmaceutical and agrochemical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a precursor for the development of organic semiconductors, conductive polymers, and advanced organic electronic materials due to its thiophene moiety.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	2-(2-Chloro-Acetylamino)-5-Phenyl-Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	379256-79-8
Molecular Formula	C15H14ClNO3S
Molecular Weight	323.79 g/mol
Synonyms	Ethyl 2-[(2-chloroacetyl)amino]-5-phenyl-3-thiophenecarboxylate; 2-[(2-Chloroacetyl)amino]-5-phenylthiophene-3-carboxylic Acid Ethyl Ester; 5-Phenyl-2-[(2-chloroacetyl)amino]thiophene-3-carboxylic Acid Ethyl Ester; 2-(2-Chloroacetamido)-5-phenylthiophene-3-carboxylic Acid Ethyl Ester; 379256-79-8; AKOS BRN 0971; AURORA KA-7245
EINECS	Contact for details

Quality Control

Our 2-(2-Chloro-Acetylamino)-5-Phenyl-Thiophene-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support development and commercial projects requiring adherence to cGMP, ISO 9001, and other relevant quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.