Description

Cycloheptanecarboxylic Acid, 1-Amino-3-Borono-, (1S)- (9Ci) is a high-purity, stereochemically defined boronic acid derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block, offering a unique combination of a chiral amino acid backbone with a reactive boronic acid functional group. It is primarily needed by pharmaceutical and agrochemical research organizations for applications in medicinal chemistry, particularly in the development of protease inhibitors and as a key intermediate in Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel therapeutic agents, especially protease inhibitors.
• Suzuki-Miyaura Cross-Coupling: Serves as a valuable boronic acid coupling partner for constructing complex biaryl and heterobiaryl structures in drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis due to its multifunctional (amino, borono, carboxyl) chiral scaffold.
• Agrochemical Synthesis: Potential intermediate in the creation of advanced, targeted crop protection molecules with specific modes of action.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying enzyme function and protein interactions.
• Asymmetric Synthesis: Employed as a chiral pool starting material or auxiliary in stereoselective synthetic routes.

Basic Information

Product Name	Cycloheptanecarboxylic Acid, 1-Amino-3-Borono-, (1S)- (9Ci)
CAS No.	379216-52-1
Molecular Formula	C8H16BNO4
Molecular Weight	201.03 g/mol
Synonyms	(1S)-1-Amino-3-boronocycloheptanecarboxylic acid; L-1-Amino-3-boronocycloheptanecarboxylic acid; (S)-1-Amino-3-boronocycloheptanecarboxylic acid; 1-Amino-3-boronocycloheptanecarboxylic acid, (S)-; Cycloheptanecarboxylic acid, 1-amino-3-borono-, (S)-; Boric acid, (S)-(1-amino-3-carboxycycloheptyl)-; A chiral boronic acid amino acid derivative
EINECS	Contact for details

Quality Control

Our Cycloheptanecarboxylic Acid, 1-Amino-3-Borono-, (1S)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data including HPLC purity, chiral purity, and NMR confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request for every batch shipped.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opened for use to prevent degradation. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.