Description

n-(2-Methoxyethyl)-2-(2-(p-Tolyloxy)Acetamido)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxamide is a sophisticated organic compound featuring a tetrahydrobenzo[b]thiophene core, strategically functionalized with acetamido and carboxamide groups. This complex molecular architecture makes it a valuable advanced pharmaceutical intermediate or a key building block in medicinal chemistry research. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents. The compound, identified by CAS No. 378769-12-1, is supplied to meet the stringent purity and consistency requirements of modern drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system or metabolic disorders.
• Medicinal Chemistry Research: Used as a high-value scaffold or building block for constructing compound libraries in structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Tool Compound: May be utilized in pharmacological research as a probe to investigate specific biological pathways or enzyme interactions.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, low-volume chemicals for research purposes.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	n-(2-Methoxyethyl)-2-(2-(p-Tolyloxy)Acetamido)-4,5,6,7-Tetrahydrobenzo[B]Thiophene-3-Carboxamide
CAS No.	378769-12-1
Molecular Formula	C21H26N2O4S
Molecular Weight	402.51 g/mol
Synonyms	N-(2-Methoxyethyl)-2-[[2-(4-methylphenoxy)acetyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide; 2-[(2-(4-Methylphenoxy)acetamido]-N-(2-methoxyethyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide; 378769-12-1; Tetrahydrobenzo[b]thiophene-3-carboxamide derivative; p-Tolyloxy acetamido tetrahydrobenzothiophene carboxamide.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and purified to meet the exacting standards of pharmaceutical research, with purity typically exceeding 97% (HPLC). Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications. We support cGMP-compliant manufacturing upon request for advanced development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.