Description

Methyl (Z)-5-(4-Acetoxyphenyl)-7-Methyl-2-((5-Methylfuran-2-Yl)Methylene)-3-Oxo-2,3-Dihydro-5H-Thiazolo[3,2-A]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and proprietary drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of target drug molecules, especially within medicinal chemistry research and development.
• API Synthesis: Used as a building block for constructing complex pharmacophores in the development of new Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to develop compounds with improved efficacy and safety profiles.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Used in university and institutional labs for investigating novel heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	Methyl (Z)-5-(4-Acetoxyphenyl)-7-Methyl-2-((5-Methylfuran-2-Yl)Methylene)-3-Oxo-2,3-Dihydro-5H-Thiazolo[3,2-A]Pyrimidine-6-Carboxylate
CAS No.	378768-09-3
Molecular Formula	C24H22N2O6S
Molecular Weight	466.51 g/mol
Synonyms	Methyl 5-(4-acetoxyphenyl)-7-methyl-2-[(5-methyl-2-furyl)methylene]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate; (Z)-Methyl 5-(4-acetoxyphenyl)-7-methyl-2-((5-methylfuran-2-yl)methylene)-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate; Thiazolopyrimidine derivative, 378768-09-3; 5H-Thiazolo[3,2-a]pyrimidine-6-carboxylic acid, 5-(4-acetoxyphenyl)-2,3-dihydro-7-methyl-2-[(5-methyl-2-furanyl)methylene]-3-oxo-, methyl ester, (Z)-; CAS 378768-09-3
EINECS	Contact for details

Quality Control

Our production of Methyl (Z)-5-(4-Acetoxyphenyl)-7-Methyl-2-((5-Methylfuran-2-Yl)Methylene)-3-Oxo-2,3-Dihydro-5H-Thiazolo[3,2-A]Pyrimidine-6-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting customer and research-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.