Description

tert-Butyl (E)-7-[3'-(4''-Fluorophenyl)-1'-methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6-heptenoate is a sophisticated synthetic intermediate characterized by its complex molecular architecture combining indole, fluorophenyl, and ester functionalities. This compound is of significant value in advanced pharmaceutical research and development, particularly for its potential role in modulating specific biological pathways. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and investigational new drugs. The precise structure offers a versatile scaffold for further chemical elaboration in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, particularly in oncology and metabolic disease research.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• API Development: Used in process chemistry for the development and scale-up of new active pharmaceutical ingredients.
• Biochemical Tool Compound: Potential use as a probe or inhibitor in biochemical assays to study enzyme or receptor function.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic services for clients.

Basic Information

Product Name	tert-Butyl (E)-7-[3'-(4''-Fluorophenyl)-1'-methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6-heptenoate
CAS No.	375846-25-6
Molecular Formula	C30H34FNO4
Molecular Weight	491.60 g/mol
Synonyms	(E)-tert-Butyl 7-(3-(1-(4-fluorophenyl)ethyl)-1H-indol-2-yl)-3-hydroxy-5-oxohept-6-enoate; 6-Heptenoic acid, 7-[3-[1-(4-fluorophenyl)ethyl]-1H-indol-2-yl]-3-hydroxy-5-oxo-, 1,1-dimethylethyl ester, (E)-; tert-Butyl (E)-7-(3-(1-(4-fluorophenyl)ethyl)-1H-indol-2-yl)-3-hydroxy-5-oxohept-6-enoate; CAS 375846-25-6
EINECS	Contact for details

Quality Control

Our high-value chemical intermediates are produced under strict quality management systems. Each batch of tert-Butyl (E)-7-[3'-(4''-Fluorophenyl)-1'-methylethyl-indol-2'-yl]-3-hydroxy-5-oxo-6-heptenoate undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request, ensuring full traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is likely light-sensitive and may be hygroscopic; therefore, handling under an inert atmosphere and desiccated conditions is recommended for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.