Description

1-(Mesitylsulfonyl)-1H-Indole is a specialized sulfonamide derivative of indole, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in its role as a versatile building block for constructing complex nitrogen- and sulfur-containing heterocycles, which are pivotal in modern pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, particularly in the synthesis of novel bioactive molecules and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting neurological disorders and cancers.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a precursor for organic electronic materials, such as charge-transport layers or light-emitting components.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces.
• Peptidomimetics & PROTACs: Utilized in the design of peptide mimics and proteolysis-targeting chimeras (PROTACs) for targeted protein degradation.
• Catalyst & Ligand Development: Acts as a scaffold for creating novel ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	1-(Mesitylsulfonyl)-1H-Indole
CAS No.	375837-81-3
Molecular Formula	C17H17NO2S
Molecular Weight	299.39 g/mol
Synonyms	1-(2,4,6-Trimethylbenzenesulfonyl)-1H-indole; 1H-Indole, 1-[(2,4,6-trimethylphenyl)sulfonyl]-; 1-Mesitylsulfonylindole; Mesitylenesulfonyl indole; Indole-1-mesitylsulfonate; 1-(2,4,6-Trimethylphenylsulfonyl)indole
EINECS	Contact for details

Quality Control

Our 1-(Mesitylsulfonyl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.