Description

10-(3,4-Dihydro-2(1H)-Isoquinolinylcarbonyl)-10H-Phenothiazine is a high-purity, advanced pharmaceutical intermediate belonging to the phenothiazine class of heterocyclic compounds. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precisely characterized material to develop new therapeutic agents and conduct structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of novel phenothiazine-derived active pharmaceutical ingredients (APIs).
• Neurological Drug Discovery: Used in the synthesis of potential therapeutic agents for central nervous system (CNS) disorders.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists to explore new chemical entities and optimize drug candidates.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry, reaction mechanisms, and pharmacological properties.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis to create complex molecules for biological screening and testing.

Basic Information

Product Name	10-(3,4-Dihydro-2(1H)-Isoquinolinylcarbonyl)-10H-Phenothiazine
CAS No.	375833-09-3
Molecular Formula	C22H18N2OS
Molecular Weight	358.46 g/mol
Synonyms	10-(1,2,3,4-Tetrahydroisoquinoline-2-carbonyl)phenothiazine; 10H-Phenothiazine-10-carboxylic acid, 1,2,3,4-tetrahydro-2-isoquinolinyl ester; N-(1,2,3,4-Tetrahydroisoquinolin-2-ylcarbonyl)phenothiazine; 375833-09-3; Phenothiazine derivative CAS 375833-09-3
EINECS	Contact for details

Quality Control

Our 10-(3,4-Dihydro-2(1H)-Isoquinolinylcarbonyl)-10H-Phenothiazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.