Description

(6-Bromobenzo[B]Thiophen-2-Yl)Methanol CAS NO 374933-76-3 is a high-purity brominated benzothiophene derivative, serving as a critical advanced intermediate in modern organic synthesis. This compound is valued for its versatile reactivity, particularly in constructing complex heterocyclic scaffolds and facilitating key coupling reactions. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the benzothiophene core's bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic semiconductors and light-emitting materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	(6-Bromobenzo[B]Thiophen-2-Yl)Methanol
CAS No.	374933-76-3
Molecular Formula	C9H7BrOS
Molecular Weight	243.12 g/mol
Synonyms	6-Bromo-2-benzothiophenemethanol; (6-Bromobenzo[b]thiophen-2-yl)methanol; 2-(Hydroxymethyl)-6-bromobenzo[b]thiophene; 6-Bromobenzo[b]thiophene-2-methanol; 6-Bromo-2-hydroxymethylbenzo[b]thiophene; 6-Bromo-2-benzothienylmethanol; 6-Bromobenzo[b]thien-2-ylmethanol; 6-Bromo-2-benzothiophen-2-ylmethanol
EINECS	Contact for details

Quality Control

Our (6-Bromobenzo[B]Thiophen-2-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.